Synthesis of a novel chiral DA-TD covalent organic framework for open-tubular capillary electrochromatography enantioseparation
Guoxiu Wang, Wenjuan Lv, Congjie Pan, Hongli Chen, Xingguo Chen
Abstract
Herein, a novel chiral covalent organic framework, DA-TD COF, with good chemical/thermal stability was synthesized and used as a chiral stationary phase for open-tubular capillary electrochromatography enantioseparation. The DA-TD COF coated capillary exhibited excellent enantioseparation efficiency and its separation efficiency did not show an obvious decrease over 200 runs. Furthermore, the enantioseparation mechanism was studied.
Topics & Concepts
Capillary electrochromatographyCovalent bondChemistryCapillary electrophoresisCapillary actionThermal stabilityChiral stationary phaseElectrochromatographyChromatographyCombinatorial chemistryChemical engineeringOrganic chemistryMaterials scienceHigh-performance liquid chromatographyEngineeringComposite materialCovalent Organic Framework ApplicationsMetal-Organic Frameworks: Synthesis and ApplicationsSupramolecular Chemistry and Complexes