Palladium-catalysed 5-<i>endo-trig</i> allylic (hetero)arylation
Bara Singh, Siddheshwar K. Bankar, Ketan Kumar, S. S. V. Ramasastry
Abstract
carbocyclisation of the tethered (π-allyl)palladium system. Further, this method was successfully applied as the key step in the total synthesis of diterpene natural products taiwaniaquinone H and dichroanone.
Topics & Concepts
Allylic rearrangementPalladiumIntramolecular forceQuaternary carbonChemistryCombinatorial chemistryCatalysisStereochemistryMedicinal chemistryOrganic chemistryEnantioselective synthesisCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsOrganoboron and organosilicon chemistry