Navigating pharmaceuticals: microfluidic devices in analytical and formulation sciences
Ankita Das, Parixit Prajapati
Abstract
Microfluidics, a growing field, involves miniaturized systems manipulating small fluid volumes through microchannels, offering unprecedented precision and efficiency. In the analytical domain, microfluidic devices have emerged as indispensable tools for pharmaceutical researchers. Their ability to operate with minimal sample volumes facilitates high-throughput screening, accelerates drug discovery processes, and enhances analytical precision. From pharmaceutical analysis to proteomics, microfluidic platforms contribute significantly to the advancement of analytical techniques. Furthermore, microfluidic devices have gained immense prominence in the field of pharmaceutical formulation sciences. Microchannels may be integrated on a variety of materials, including silicon, glass, polymethylmethacrylate, polydimethylsiloxane and silicon dioxide allows for precise control over formulation processes. These devices enable researchers to optimize drug formulations, ensuring uniformity, stability, and controlled release characteristics. The envisaged impact includes streamlined drug development pipelines, improved therapeutic outcomes, and the potential for on-demand personalized medicine formulations. The present work explores current applications of microfluidic devices in drug screening, drug development, in advancing analytical techniques and their potential to revolutionize pharmaceutical formulation strategies.