Small molecules with tetrahydroquinoline-containing Povarov scaffolds as inhibitors disrupting the Protein–RNA interaction of LIN28–let-7
Georg L. Goebel, Lisa Hohnen, Lydia Borgelt, Pascal Hommen, Xiaqiu Qiu, Helen L. Lightfoot, Peng Wu
Topics & Concepts
ChemistryLIN28MoietyCold-shock domainMoleculeCombinatorial chemistrySmall moleculeRNAStereochemistryBiochemistryOrganic chemistryTranscription factorSOX2GenePlant Virus Research StudiesImmune Cell Function and InteractionRNA Research and Splicing