A chemo-enzymatic tandem reaction in a mixture of deep eutectic solvent and water in continuous flow
Bianca Grabner, Anna Katharina Schweiger, Kristian Gavric, Robert Kourist, Heidrun Gruber‐Wölfler
Abstract
Deep eutectic solvent (DES) enables drastic increase in substrate solubility and solvent compatibility of a chemo-enzymatic two-step flow process combining enzymatic decarboxylation and Pd-catalyzed Heck coupling.
Topics & Concepts
Deep eutectic solventTandemEutectic systemSolventChemistryFlow (mathematics)Continuous flowChromatographyMaterials scienceOrganic chemistryMechanicsBiochemical engineeringEngineeringComposite materialAlloyPhysicsInnovative Microfluidic and Catalytic Techniques InnovationEnzyme Catalysis and ImmobilizationIonic liquids properties and applications