Glucocorticoid caused lactic acid accumulation and damage in human chondrocytes via ROS-mediated inhibition of Monocarboxylate Transporter 4
Qingxian Li, Haitao Chen, Zhenyu Li, Fan Zhang, Liaobin Chen
Topics & Concepts
CartilageReactive oxygen speciesChemistryIn vivoOxidative stressApoptosisAggrecanInternal medicineCell biologyEndocrinologyPharmacologyBiochemistryOsteoarthritisBiologyMedicineAnatomyPathologyBiotechnologyAlternative medicineArticular cartilageOsteoarthritis Treatment and MechanismsPeroxisome Proliferator-Activated ReceptorsChemokine receptors and signaling