Tetranuclear and trinuclear copper(<scp>i</scp>) pyrazolates as catalysts in copper mediated azide–alkyne cycloadditions (CuAAC)
Monika R. Patterson, H. V. Rasika Dias
Abstract
Tetranuclear copper complexes are very competent catalysts for the azide–alkyne cycloadditions. Related trinuclear species supported by electron-rich pyrazolates are notably less effective mediators of this reaction under the same conditions.
Topics & Concepts
CopperHomolepticChemistrySteric effectsCatalysisCycloadditionAlkyneAzideLigand (biochemistry)Polymer chemistryStereochemistryMedicinal chemistryCrystallographyOrganic chemistryMetalReceptorBiochemistryClick Chemistry and ApplicationsCO2 Reduction Techniques and CatalystsSynthesis and Catalytic Reactions