Design, synthesis, and biological evaluation of 1,6-naphthyridine-2-one derivatives as novel FGFR4 inhibitors for the treatment of colorectal cancer
Bo Fang, Yinshuang Lai, Hao Yan, Yue Ma, Zefeng Ni, Qianqian Zhu, Jianxia Zhang, Yanfei Ye, Mengying Wang, Peipei Wang, Yan Wang, Shuyuan Zhang, Min Hui, Dalong Wang, Yunjie Zhao, Xiaokun Li, Kun Wang, Zhiguo Liu, Yunjie Zhao, Xiaokun Li, Kun Wang, Zhiguo Liu
Topics & Concepts
ChemistryColorectal cancerCancerCancer researchKinasePharmacologyBiochemistryInternal medicineMedicineFibroblast Growth Factor ResearchKruppel-like factors researchProtein Tyrosine Phosphatases