Up-regulation of the p75 neurotrophin receptor is an essential mechanism for HIV-gp120 mediated synaptic loss in the striatum
Andrew Speidell, Gino Paolo Asuni, Renee Wakulski, Italo Mocchetti
Topics & Concepts
Dendritic spineBiologyNeuroscienceLow-affinity nerve growth factor receptorCell biologyStriatumNeurotrophinBrain-derived neurotrophic factorTropomyosin receptor kinase BMedium spiny neuronSynapseNeurotrophic factorsSynaptic plasticityGenetically modified mouseReceptorTransgeneHippocampal formationBiochemistryGeneDopamineHIV Research and TreatmentNerve injury and regenerationHerpesvirus Infections and Treatments