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Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice

Yi Xu, Kun Cao, Bing Guo, Jie Xiang, Yang‐Ting Dong, Xiaolan Qi, Wenfeng Yu, Yan Xiao, Zhi‐Zhong Guan

2020Aging22 citationsDOIOpen Access PDF

Abstract

mice, which might help explain the impaired cognition in T2DM.

Topics & Concepts

HippocampusEndocrinologyAcetylcholineInternal medicineAcetylcholine receptorType 2 Diabetes MellitusReceptorNicotinic agonistDiabetes mellitusApoptosisMedicineNeuroscienceChemistryPsychologyBiochemistryNicotinic Acetylcholine Receptors StudyCholinesterase and Neurodegenerative DiseasesReceptor Mechanisms and Signaling
Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice | Litcius