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Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects

Emily Fabyanic, Peng Hu, Qi Qiu, Kiara N. Berríos, Daniel Connolly, Tong Wang, Jennifer Flournoy, Zhaolan Zhou, Rahul M. Kohli, Hao Wu

2023Nature Biotechnology45 citationsDOIOpen Access PDF

Topics & Concepts

Biology5-Methylcytosine5-HydroxymethylcytosineComputational biologyEpigeneticsGeneDNA methylationGeneticsGene expressionEpigenetics and DNA MethylationSingle-cell and spatial transcriptomicsRNA modifications and cancer
Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects | Litcius