ROS-Scavenging Selenofluoxetine Derivatives Inhibit <i>In Vivo</i> Serotonin Reuptake
Giovanni Ribaudo, Marco Bortoli, Colby E. Witt, Brenna Parke, Sergio Mena, Erika Oselladore, Giuseppe Zagotto, Parastoo Hashemi, Laura Orian
Abstract
in mice. We therefore present a frontier dual strategy that paves the way for the future of antidepressant therapies.
Topics & Concepts
FluoxetineAntidepressantOxidative stressSerotoninPharmacologyReuptake inhibitorChemistryAntioxidantReuptakeNeurochemistryIn vivoSerotonin reuptake inhibitorDepression (economics)MedicineBiochemistryPsychologyNeuroscienceBiologyInternal medicineHippocampusMacroeconomicsBiotechnologyReceptorNeurologyEconomicsTryptophan and brain disordersOrganoselenium and organotellurium chemistryMaternal Mental Health During Pregnancy and Postpartum