Can’t handle the itch? Refractory immunotherapy-related transient acantholytic dermatosis: prompt resolution with dupilumab

Abstract

Transient acantholytic dermatosis (TAD; Grover disease) is an inflammatory immune condition characterized by small, erythematous papules most commonly affecting the trunk and extremities of middle-aged men with a history of sun exposure. Skin pathology characteristically demonstrates acantholytic dyskeratosis within the epidermis with varying degrees of associated dermal inflammation, often with eosinophils. Lesions typically last for weeks to months, though there is a propensity for recurrence.

Topics & Concepts