6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming
Jun Cao, Xiaosong Sun, Xuejun Zhang, Dehong Chen
Topics & Concepts
MedicineAMPKCancer researchGene knockdownDownregulation and upregulationGrowth inhibitionPentose phosphate pathwayCell growthPharmacologyInternal medicineApoptosisEnzymeBiologyBiochemistryGlycolysisMetabolismGeneProtein kinase ACancer, Hypoxia, and MetabolismBiochemical and Molecular ResearchAldose Reductase and Taurine