Lophiostomin A–D: new 3,4-dihydroisocoumarin derivatives from the endophytic fungus <i>Lophiostoma</i> sp. Sigrf10
Ziling Mao, Mengyao Xue, Gan Gu, Weixuan Wang, Dianpeng Li, Daowan Lai, Ligang Zhou
Abstract
Four new 3,4-dihydroisocoumarin congeners, named lophiostomin A–D (<bold>1–4</bold>), together with two known α-pyridones (<bold>5</bold> and <bold>6</bold>) were isolated from cultures of the endophytic fungus <italic>Lophiostoma</italic> sp. Sigrf10 obtained from <italic>Siraitia grosvenorii</italic>.
Topics & Concepts
FungusPlant use of endophytic fungi in defenseBotanyStereochemistryChemistryBiologyMicrobial Natural Products and BiosynthesisSynthesis and Biological ActivityMarine Sponges and Natural Products