Cell Membrane-Cloaked Nanotherapeutics for Targeted Drug Delivery
Na‐Hyun Lee, Sumin You, Ali Taghizadeh, Mohsen Taghizadeh, Hye Sung Kim
Abstract
Cell membrane cloaking technique is bioinspired nanotechnology that takes advantage of naturally derived design cues for surface modification of nanoparticles. Unlike modification with synthetic materials, cell membranes can replicate complex physicochemical properties and biomimetic functions of the parent cell source. This technique indeed has the potential to greatly augment existing nanotherapeutic platforms. Here, we provide a comprehensive overview of engineered cell membrane-based nanotherapeutics for targeted drug delivery and biomedical applications and discuss the challenges and opportunities of cell membrane cloaking techniques for clinical translation.
Topics & Concepts
NanotechnologyDrug deliveryCellNanomedicineMembraneTargeted drug deliveryCell membraneChemistryMaterials scienceNanoparticleBiochemistryGold and Silver Nanoparticles Synthesis and ApplicationsNanoparticle-Based Drug DeliveryAdvanced biosensing and bioanalysis techniques