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Applying the adverse outcome pathway concept for assessing non-monotonic dose responses: biphasic effect of bis(2-ethylhexyl) phthalate (DEHP) on testosterone levels

Maria Chiara Astuto, D. Benford, Laurent Bodin, I. Cattaneo, Þórhallur I. Halldórsson, J. Schlatter, Richard M. Sharpe, José Tarazona, Mamoun Younes

2022Archives of Toxicology29 citationsDOI

Topics & Concepts

PhthalateDibutyl phthalateAdverse effectTestosterone (patch)Adverse Outcome PathwayRisk assessmentBenzhydryl compoundsMedicinePsychologyPhysiologyToxicologyEndocrinologyPharmacologyInternal medicineChemistryBiologyBisphenol AComputer scienceComputational biologyComputer securityOrganic chemistryEpoxyEffects and risks of endocrine disrupting chemicalsAnimal testing and alternativesToxic Organic Pollutants Impact
Applying the adverse outcome pathway concept for assessing non-monotonic dose responses: biphasic effect of bis(2-ethylhexyl) phthalate (DEHP) on testosterone levels | Litcius