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Exposure to di-(2-ethylhexyl) phthalate reduces secretion of GDNF via interfering with estrogen pathway and downregulating ERK/c-fos signaling pathway in astrocytes

Jianan Wang, Xudong Li, Chaonan Wang, Yan Li, Jinmiao Wang, Rui Fang, Jingsi Wang, Jie Chen, Jing Dong

2021Food and Chemical Toxicology21 citationsDOI

Topics & Concepts

Glial cell line-derived neurotrophic factorMAPK/ERK pathwayPhthalateEndocrinologyInternal medicineChemistrySignal transductionEstrogenBiologyNeurotrophic factorsMedicineBiochemistryReceptorOrganic chemistryNuclear Receptors and SignalingNeurological Disease Mechanisms and Treatments
Exposure to di-(2-ethylhexyl) phthalate reduces secretion of GDNF via interfering with estrogen pathway and downregulating ERK/c-fos signaling pathway in astrocytes | Litcius