NLRP3 inflammasome and glia maturation factor coordinately regulate neuroinflammation and neuronal loss in MPTP mouse model of Parkinson’s disease
Hayate Javed, Ramasamy Thangavel, Govindhasamy Pushpavathi Selvakumar, Iuliia Dubova, Noah Schwartz, Mohammad Ejaz Ahmed, Smita Zaheer, Duraisamy Kempuraj, Shankar S. Iyer, Asgar Zaheer, Mohammad Moshahid Khan
Topics & Concepts
MPTPNeuroinflammationInflammasomeMicrogliaSubstantia nigraNeurodegenerationDopaminergicParkinson's diseaseNeuroprotectionProinflammatory cytokinePars compactaBiologyChemistryCell biologyNeuroscienceInflammationImmunologyMedicineDopamineInternal medicineDiseaseNeuroinflammation and Neurodegeneration MechanismsInflammasome and immune disordersAdenosine and Purinergic Signaling