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Design, synthesis and biological evaluation of novel O-carbamoyl ferulamide derivatives as multi-target-directed ligands for the treatment of Alzheimer’s disease

Zhipei Sang, Keren Wang, Ping Bai, Anguo Wu, Jian Shi, Wenmin Liu, Gaofeng Zhu, Yiling Wang, Yu Lan, Zude Chen, Yiyang Zhao, Zhanpin Qiao, Changning Wang, Zhenghuai Tan

2020European Journal of Medicinal Chemistry50 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryPharmacologyIn vivoIC50In vitroMicrosomeLead compoundBiochemistryMedicineBiotechnologyBiologyCholinesterase and Neurodegenerative DiseasesMedicinal Plants and NeuroprotectionAlzheimer's disease research and treatments
Design, synthesis and biological evaluation of novel O-carbamoyl ferulamide derivatives as multi-target-directed ligands for the treatment of Alzheimer’s disease | Litcius