Synthesis, characterization and investigation of synergistic antibacterial activity and cell viability of silver–sulfur doped graphene quantum dot (Ag@S-GQDs) nanocomposites
Sachin Kadian, Gaurav Manik, Neeladrisingha Das, Poonam Nehra, R. P. Chauhan, Partha Roy
Abstract
of the Ag@S-GQDs nanocomposite were found to be sufficient to hinder the growth of P. aeruginosa and S. aureus. A fractional inhibition concentration (FIC) index below 0.5 confirmed the existence of a synergistic effect between AgNPs and S-GQDs in the Ag@S-GQDs nanocomposite. In addition, the cytotoxicity of the Ag@S-GQDs nanocomposite, AgNPs and S-GQDs was also investigated using HEK 293 cell lines. Interestingly, the Ag@S-GQDs nanocomposite exhibited superior cell viability as compared to AgNPs and S-GQDs. These improved antibacterial and biocompatibility data demonstrate that the Ag@S-GQDs nanocomposite can serve as a promising antibacterial agent for industry to fabricate next-generation self-sterile textiles, antibacterial coatings and useful health care products supporting cell viability.