Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection
Joel Selkrig, Nan Li, Annika Hausmann, Matthew Mangan, Matylda Zietek, André Mateus, Jacob Bobonis, Anna Sueki, Haruna Imamura, Bachir El Debs, Gianluca Sigismondo, Bogdan I. Florea, Herman S. Overkleeft, Nataša Kopitar‐Jerala, Boris Turk, Pedro Beltrão, Mikhail M. Savitski, Eicke Latz, Wolf‐Dietrich Hardt, Jeroen Krijgsveld, Athanasios Typas
Topics & Concepts
CathepsinProteomeSalmonella entericaBiologyCell biologyCathepsin BCathepsin LProgrammed cell deathInflammasomePyroptosisIntracellular parasiteCathepsin SProteomicsIntracellularBiochemistryInflammationImmunologyApoptosisEscherichia coliGeneEnzymeInflammasome and immune disordersStreptococcal Infections and Treatmentsinterferon and immune responses