Ester-directed orthogonal dual C–H activation and <i>ortho</i> aryl C–H alkenylation <i>via</i> distal weak coordination
Manickam Bakthadoss, Tadiparthi Thirupathi Reddy, Vishal Agarwal, Duddu S. Sharada
Abstract
An orthogonal cross-coupling between aromatic C(sp 2 ) and aliphatic olefinic C(sp 2 ) carbons of two same molecules via dual C–H activation and ortho C–H olefination with various alkenes via distal ester directing group has been developed for the first time.
Topics & Concepts
ArylChemistryFunctional groupIntermolecular forceMoleculeSubstrate (aquarium)StereochemistryCinnamic acidCombinatorial chemistryMedicinal chemistryOrganic chemistryAlkylPolymerGeologyOceanographyCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesSynthesis and Catalytic Reactions