Novel indole derivatives targeting HuR-mRNA complex to counteract high glucose damage in retinal endothelial cells
Chiara Bianca Maria Platania, Valeria Pittalà, Alessia Pascale, Nicoletta Marchesi, Carmelina Daniela Anfuso, Gabriella Lupo, Martina Cristaldi, Melania Olivieri, Francesca Lazzara, Luisa Di Paola, Filippo Drago, Claudio Bucolo
Topics & Concepts
Messenger RNADiabetic retinopathyRetinalWestern blotChemistryIn vitroMolecular biologyTumor necrosis factor alphaVascular endothelial growth factorElectrophoretic mobility shift assayGene expressionBiologyVEGF receptorsImmunologyBiochemistryEndocrinologyCancer researchGeneDiabetes mellitusRNA Research and SplicingRNA Interference and Gene Deliveryinterferon and immune responses