Development of in silico methodology for siRNA lipid nanoparticle formulations
Haoshi Gao, Stanislav Kan, Zhuyifan Ye, Yuchen Feng, Lei Jin, Xudong Zhang, Jiayin Deng, Ging Chan, Yuanjia Hu, Yongjun Wang, Dongsheng Cao, Yuanhui Ji, Mingtao Liang, Haifeng Li, Defang Ouyang
Topics & Concepts
In silicoSmall interfering RNAGene knockdownGene silencingComputational biologyRNA interferenceRational designIn vivoChemistryComputer scienceNanotechnologyBiologyRNABiotechnologyMaterials scienceBiochemistryGeneRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesDendrimers and Hyperbranched Polymers