A general strategy for designing NIR-II emissive silk for the <i>in vivo</i> monitoring of an implanted stent model beyond 1500 nm
Zhiming Deng, Junqing Huang, Zhenluan Xue, Mingyang Jiang, Youbin Li, Songjun Zeng
Abstract
nanocrystals. After being fed lanthanide nanocrystals, the silk spun by silkworms shows efficient NIR-II emission beyond 1500 nm. Moreover, NIR-II bio-imaging guided biological stent model monitoring presents a superior signal-to-noise (S/N) ratio compared to the traditional optical imaging by utilizing the upconversion (UC) region. These findings open up the possibility of designing NIR-II optically functionalized silk materials for highly sensitive and deep-tissue monitoring of the in vivo states of the implanted devices.
Topics & Concepts
FibroinSILKPhoton upconversionMaterials scienceIn vivoBiocompatible materialNanotechnologyNear-infrared spectroscopyLanthanideBiomedical engineeringOptoelectronicsLuminescenceChemistryComposite materialOpticsOrganic chemistryIonMedicineBiologyBiotechnologyPhysicsSilk-based biomaterials and applicationsQuantum Dots Synthesis And PropertiesNeurobiology and Insect Physiology Research