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ID1 overexpression increases gefitinib sensitivity in non-small cell lung cancer by activating RIP3/MLKL-dependent necroptosis

Hor‐Yue Tan, Ning Wang, Yau-Tuen Chan, Cheng Zhang, Wei Guo, Feiyu Chen, Zhangfeng Zhong, Sha Li, Yibin Feng

2020Cancer Letters42 citationsDOI

Topics & Concepts

GefitinibNecroptosisCancer researchLung cancerKRASEpidermal growth factor receptorApoptosisMedicineTyrosine kinaseKinaseProgrammed cell deathCancerBiologyInternal medicineReceptorCell biologyBiochemistryColorectal cancerCell death mechanisms and regulationNF-κB Signaling PathwaysLung Cancer Treatments and Mutations
ID1 overexpression increases gefitinib sensitivity in non-small cell lung cancer by activating RIP3/MLKL-dependent necroptosis | Litcius