Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro
Asha Rizor, Edward Pajarillo, Ivan Nyarko‐Danquah, Alexis Digman, Leyah Mooneyham, Deok‐Soo Son, Michael Aschner, Eun-Sook Lee
Topics & Concepts
IκB kinaseOxidative stressKinaseReactive oxygen speciesCell biologyDownregulation and upregulationChemistryBiologySignal transductionBiochemistryNF-κBGeneNF-κB Signaling PathwaysNeuroscience and Neuropharmacology ResearchTrace Elements in Health