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Mutations in the Hsp90 N Domain Identify a Site that Controls Dimer Opening and Expand Human Hsp90α Function in Yeast

Michael Reidy, Daniel C. Masison

2020Journal of Molecular Biology14 citationsDOIOpen Access PDF

Topics & Concepts

Hsp90YeastATP hydrolysisChaperone (clinical)Saccharomyces cerevisiaeFunction (biology)ATPaseBiologyBiochemistryCyclic nucleotide-binding domainCell biologyNucleotideChemistryHeat shock proteinEnzymeGeneMedicinePathologyHeat shock proteins researchProtein Structure and DynamicsEnzyme Structure and Function
Mutations in the Hsp90 N Domain Identify a Site that Controls Dimer Opening and Expand Human Hsp90α Function in Yeast | Litcius