Using Human Induced Pluripotent Stem Cell–Derived Organoids to Identify New Pathologies in Patients With PDX1 Mutations
Mansa Krishnamurthy, Daniel O. Kechele, Taylor Broda, Xinghao Zhang, Jacob R. Enriquez, Heather A. McCauley, J. Guillermo Sanchez, Kyle W. McCracken, Joseph Palermo, Anas Bernieh, Margaret H. Collins, Inas H. Thomas, H Neef, Amer Heider, Andrew Dauber, James M. Wells
Topics & Concepts
Induced pluripotent stem cellOrganoidPDX1Stem cellEnteroendocrine cellBiologyPathologyStomachEmbryonic stem cellMedicineInternal medicineCell biologyEndocrine systemGeneticsIsletInsulinGeneHormonePancreatic function and diabetesPluripotent Stem Cells ResearchCongenital heart defects research