α-Synuclein Overexpression Induces Lysosomal Dysfunction and Autophagy Impairment in Human Neuroblastoma SH-SY5Y
Ana Carolina Nascimento, Adolfo Garcia Erustes, Patrícia Reckziegel, Cláudia Bincoletto, Rodrigo Portes Ureshino, Gustavo J.S. Pereira, Soraya S. Smaili
Topics & Concepts
AutophagyNeurodegenerationEndoplasmic reticulumLAMP1NeuroprotectionSH-SY5YCell biologyMutantBiologyLysosomeGene isoformIntracellularChemistryBiochemistryNeuroblastomaInternal medicineGeneNeuroscienceCell cultureGeneticsApoptosisMedicineDiseaseEnzymeParkinson's Disease Mechanisms and TreatmentsCalcium signaling and nucleotide metabolismAutophagy in Disease and Therapy