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Tri-omic single-cell mapping of the 3D epigenome and transcriptome in whole mouse brains throughout the lifespan

Haoxi Chai, Xingyu Huang, Guangzhou Xiong, Jiaxiang Huang, Katarzyna Pels, Lingyun Meng, Jin Han, Dongmei Tang, Guanjing Pan, Liang Deng, Qin Xiao, Xiaotao Wang, Meng Zhang, Krzysztof Banecki, Dariusz Plewczyński, Chia‐Lin Wei, Yijun Ruan

2025Nature Methods19 citationsDOIOpen Access PDF

Topics & Concepts

EpigenomeTranscriptomeBiologyComputational biologyCell biologyGeneticsDNA methylationGene expressionGeneSingle-cell and spatial transcriptomicsCell Image Analysis TechniquesRNA Research and Splicing
Tri-omic single-cell mapping of the 3D epigenome and transcriptome in whole mouse brains throughout the lifespan | Litcius