A bio-ionic liquid based self-healable and adhesive ionic hydrogel for the on-demand transdermal delivery of a chemotherapeutic drug
Raviraj Pansuriya, James Doutch, Bhagyesh Parmar, Suresh Kumar Kailasa, Najet Mahmoudi, Clare Hoskins, Naved I. Malek
Abstract
cytotoxicity that was considerably affected by the 5-FU-loaded hydrogel. These results indicate the potential of the hydrogel as a transdermal drug delivery vehicle for the treatment of breast cancer.
Topics & Concepts
TransdermalIonic liquidDrug deliveryAdhesiveChemotherapeutic drugsSelf-healing hydrogelsOn demandIonic bondingMaterials scienceDrugChemistryNanotechnologyPharmacologyComputer sciencePolymer chemistryOrganic chemistryMedicineMultimediaLayer (electronics)IonCatalysisBiochemistryApoptosisAdvancements in Transdermal Drug DeliveryAdvanced Drug Delivery SystemsLipid Membrane Structure and Behavior