Strategies to improve regenerative potential of mesenchymal stem cells
Mahmood S. Choudhery
Abstract
expansion", "donor age" and "donor disease status" for their successful autologous use. The current review has been organized to address the age and disease depleted function of resident adult stem cells, and the strategies to improve their potential. To combat the problem of decline in the regenerative potential of cells, this review focuses on the strategies that manipulate the cell environment such as hypoxia, heat shock, caloric restriction and preconditioning with different factors.
Topics & Concepts
Stem cellMesenchymal stem cellRegenerative medicineMedicineAdult stem cellPopulationClinical uses of mesenchymal stem cellsImmunologyBiologyCell biologyPathologyEndothelial stem cellIn vitroBiochemistryEnvironmental healthPancreatic function and diabetesMesenchymal stem cell researchTissue Engineering and Regenerative Medicine