Physiological impacts of computed tomography airway dysanapsis, fractal dimension, and branch count in asymptomatic never smokers
Tomoki Maetani, Naoya Tanabe, Satoru Terada, Yusuke Shiraishi, Hiroshi Shima, Shizuo Kaji, Ryo Sakamoto, Tsuyoshi Oguma, Susumu Satô, Izuru Masuda, Toyohiro Hirai
Abstract
This study showed that fractal dimension and total airway count of the airway tree on computed tomography are associated with lung function on spirometry independent of a smaller airway for a given lung size (dysanapsis) in asymptomatic never smokers without a history of lung diseases. In addition to dysanapsis, the morphometric complexity of the airway tree and the airway branch count may cause a substantial variation of lung function in these subjects.
Topics & Concepts
AsymptomaticComputed tomographyAirwayFractal dimensionMedicineFractalTomographyRadiologyInternal medicineMathematicsSurgeryMathematical analysisChronic Obstructive Pulmonary Disease (COPD) ResearchRespiratory Support and MechanismsInhalation and Respiratory Drug Delivery