Studying mutation rate evolution in primates—the effects of computational pipelines and parameter choices
Susanne P. Pfeifer
Abstract
This commentary investigates the important role of computational pipeline and parameter choices in performing mutation rate estimation, using the recent article published in this journal by Bergeron et al. entitled "The germline mutational process in rhesus macaque and its implications for phylogenetic dating" as an illustrative example.
Topics & Concepts
Mutation rateMutationComputer scienceComputational biologyEvolutionary biologyBiologyGeneticsGeneEvolution and Genetic DynamicsGenomics and Rare DiseasesCRISPR and Genetic Engineering