Human CD4+CD25+ T cells expressing a chimeric antigen receptor against aberrant superoxide dismutase 1 trigger antigen-specific immunomodulation
David J. Graber, W. James Cook, Marie-Louise Sentman, Joana M. Murad-Mabaera, Charles L. Sentman
Topics & Concepts
NeuroinflammationBiologyAntigenFOXP3CD28ImmunologyTumor necrosis factor alphaMolecular biologyImmune systemInflammationCD8Amyotrophic Lateral Sclerosis ResearchCAR-T cell therapy researchNeuroinflammation and Neurodegeneration Mechanisms