A novel cerium(<scp>iii</scp>)–isatin Schiff base complex: spectrofluorometric and DFT studies and application as a kidney biomarker for ultrasensitive detection of human creatinine
Sheta M. Sheta, Magda A. Akl, Heba E. Saad, El-Sayed R. H. El-Gharkawy
Abstract
) was found to be 0.9890. The PL spectra indicate that C1 has high selectivity toward creatinine without interference from other different analytes and can be successfully used as an optical sensor for creatinine detection. The mechanism of quenching between the Ce(iii) complex and creatinine was a dynamic type. The geometry of Schiff base L1 and its cerium(iii) complex C1 was proven by using density functional theory (DFT). The energy of the LUMO and HOMO, energy gap, dipole moment and structure-activity relationship were determined and confirmed.
Topics & Concepts
Schiff baseIsatinChemistryCeriumDetection limitPhotoluminescenceProton NMRAnalytical Chemistry (journal)Materials scienceInorganic chemistryChromatographyCrystallographyStereochemistryOrganic chemistryOptoelectronicsMolecular Sensors and Ion DetectionElectrochemical sensors and biosensorsLanthanide and Transition Metal Complexes