Synthesis, crystal structure and antibacterial studies of dihydropyrimidines and their regioselectively oxidized products
Alakbar Huseynzada, Christian Jelch, Haji Vahid Akhundzada, Sarra Soudani, Chérif Ben Nasr, Aygun Israyilova, Filippo Doria, Ulviyya Hasanova, Rana F. Khankishiyeva, Mauro Freccero
Abstract
Known methods of synthesis of dihydropyrimidines and their oxidized products were modified, the impact of hydrogen bonds on stabilization of preferred tautomer and biological activities were studied.
Topics & Concepts
ChemistryBiginelli reactionRegioselectivityOxidizing agentHydrogen bondTautomerCatalysisOrganic chemistryMoleculeMulticomponent Synthesis of HeterocyclesSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds