An updated calculator for determining levodopa-equivalent dose
Dag Nyholm, Wolfgang H. Jost
Abstract
Calculation of levodopa-equivalent dose in Parkinson's disease has become common in research, but is also a useful tool in clinical practice, especially when initiating device-aided treatments (deep brain stimulation, apomorphine and levodopa infusions). The aim with the present calculator is to provide an updated conversion table, including dose calculation of the recently developed levodopa/entacapone/carbidopa intestinal gel infusion. Future versions of the calculator should be made conducive to learning by means of artificial intelligence.
Topics & Concepts
LevodopaEntacaponeCalculatorApomorphineParkinson's diseaseCarbidopaComputer scienceMedicineBenserazideMedical physicsDiseaseDopamineInternal medicineDopaminergicOperating systemParkinson's Disease Mechanisms and TreatmentsNeurological disorders and treatmentsGenetic Neurodegenerative Diseases