Spatially resolved genome-wide joint profiling of epigenome and transcriptome with spatial-ATAC-RNA-seq and spatial-CUT&Tag-RNA-seq

Haikuo Li, Shuozhen Bao, Negin Farzad, Xiaoyu Qin, Anthony A. Fung, Di Zhang, Zhiliang Bai, Bo Tao, Rong Fan

2025Nature Protocols30 citationsDOI

Topics & Concepts

EpigenomeTranscriptomeBiologyEpigenomicsComputational biologyChromatinRNA-SeqRNATiling arrayDNA microarrayGeneticsGeneGene expressionDNA methylationSingle-cell and spatial transcriptomicsAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic Engineering

Spatially resolved genome-wide joint profiling of epigenome and transcriptome with spatial-ATAC-RNA-seq and spatial-CUT&amp;Tag-RNA-seq

Topics & Concepts

Spatially resolved genome-wide joint profiling of epigenome and transcriptome with spatial-ATAC-RNA-seq and spatial-CUT&Tag-RNA-seq