Tablysin-15 inhibits osteoclastogenesis and LPS-induced bone loss via attenuating the integrin αvβ3 pathway
Qingye Zeng, Wancheng Lu, Zhenhui Deng, Jiena Wu, Ruiyin Guo, Xueqing Xu
Topics & Concepts
OsteoclastRANKLBone resorptionCell biologyChemistryIntegrinMAPK/ERK pathwayCancer researchProtein kinase BSignal transductionOsteoporosisOsteolysisPodosomeNF-κBIn vitroInternal medicineCellActivator (genetics)BiologyMedicineReceptorBiochemistryCytoskeletonSurgeryBone Metabolism and DiseasesCell Adhesion Molecules ResearchBone health and treatments