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Synthesis and in vitro/in vivo anticancer evaluation of pentacyclic triterpenoid derivatives linked with -phenylalanine or -proline

Yudong Yin, Lixin Sheng, Juzheng Zhang, Liqiong Zhang, Jingjing Liu, Xiaoan Wen, Yanghan Liu, Yang Si, Keguang Cheng

2022Bioorganic Chemistry18 citationsDOI

Topics & Concepts

ChemistryPhenylalanineIn vivoApoptosisProlineBiochemistryIn vitroUrsolic acidBioavailabilityWestern blotOleanolic acidIC50Aromatic amino acidsPharmacologyAmino acidStereochemistryBiologyChromatographyMedicineGeneAlternative medicineBiotechnologyPathologyPharmacological Effects of Natural CompoundsNatural product bioactivities and synthesisPlant biochemistry and biosynthesis
Synthesis and in vitro/in vivo anticancer evaluation of pentacyclic triterpenoid derivatives linked with -phenylalanine or -proline | Litcius