Synthesis and in vitro/in vivo anticancer evaluation of pentacyclic triterpenoid derivatives linked with -phenylalanine or -proline
Yudong Yin, Lixin Sheng, Juzheng Zhang, Liqiong Zhang, Jingjing Liu, Xiaoan Wen, Yanghan Liu, Yang Si, Keguang Cheng
Topics & Concepts
ChemistryPhenylalanineIn vivoApoptosisProlineBiochemistryIn vitroUrsolic acidBioavailabilityWestern blotOleanolic acidIC50Aromatic amino acidsPharmacologyAmino acidStereochemistryBiologyChromatographyMedicineGeneAlternative medicineBiotechnologyPathologyPharmacological Effects of Natural CompoundsNatural product bioactivities and synthesisPlant biochemistry and biosynthesis