Caffeine Inhibits Activation of the NLRP3 Inflammasome via Autophagy to Attenuate Microglia-Mediated Neuroinflammation in Experimental Autoimmune Encephalomyelitis
Huiqi Wang, Kai-Yi Song, Jinzhou Feng, Siyuan Huang, Xiuming Guo, Lei Zhang, Gang Zhang, Yingchao Huo, Rongrong Zhang, Yue Ma, Qingzhe Hu, Xinyue Qin
Topics & Concepts
AutophagyInflammasomeMicrogliaExperimental autoimmune encephalomyelitisNeuroinflammationATG5CaffeineProinflammatory cytokineInflammationEncephalomyelitisChemistryImmunologyPharmacologyCell biologyBiologyBiochemistryMultiple sclerosisEndocrinologyApoptosisAutophagy in Disease and TherapyInflammasome and immune disordersCalcium signaling and nucleotide metabolism