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Differential expression of BMP/SMAD signaling and ovarian-associated genes in the granulosa cells of FecB introgressed GMM sheep

Satish Kumar, Pradeep Kumar Rajput, S.V. Bahire, Basanti Jyotsana, Vijay Kumar, Davendra Kumar

2020Systems Biology in Reproductive Medicine17 citationsDOIOpen Access PDF

Abstract

in granulosa cells of newly developed GMM ewes. ABBREVIATIONS: : Booroola fecundity; BMPR: Bone morphogenetic protein receptor; CYP11A1: Cytochrome P450 family 11 subfamily A member 1; StAR (Steroidogenic acute regulatory protein); 3βHSD1: 3 Beta-hydroxysteroid dehydrogenase; IGF: Insulin-like growth factor; ActR2: Activin receptor 2; ACVR1: Activin A receptor, type I; ACVR2: Activin A receptor, type II; ACVRL1: Activin A receptor like type 1; ACVR1B: Activin A receptor type 1B; ACVR1C: Activin A receptor type 1C; RFLP-PCR: Restriction fragment length polymorphism-polymerase chain reaction; qRT-PCR: Quantitative real-time PCR; ANOVA: Analysis of variance; P4R: Progesterone receptor: AMH: Anti mullerian hormone; RT-PCR: Reverse transcriptase-polymerase chain reaction; ER: Estrogen receptor; FSHR: Follicle stimulating hormone receptor.

Topics & Concepts

SMADBiologyBone morphogenetic proteinBone morphogenetic protein 2Bone morphogenetic protein 15EndocrinologyAndrologyInternal medicineTransforming growth factorGeneGeneticsBone morphogenetic protein 7MedicineIn vitroReproductive Biology and FertilityRenal and related cancersTGF-β signaling in diseases
Differential expression of BMP/SMAD signaling and ovarian-associated genes in the granulosa cells of FecB introgressed GMM sheep | Litcius