Antiplasmodial Activity and Phytochemical Constituents of Selected Antimalarial Plants Used by Native People in West Timor Indonesia
Maximus M. Taek, Gerardus D. Tukan, Bambang Prajogo, Mangestuti Agil
Abstract
OBJECTIVES: To document traditional antimalarial plants used by Tetun ethnic people in West Timor Indonesia and evaluate the antiplasmodial activity and phytochemicals of several plants that are widely used as oral medicine. MATERIALS AND METHODS: were tested. Gas chromatography-mass spectrometry instrument was used to analyze the phytochemicals of the extracts. RESULTS: values of 54.25, 63.52, 63.91, and 66.49 μg/mL, respectively. The phytochemicals identification data indicate that these 11 plants contain alkaloids, terpenoids, steroids, coumarins, alcohols, thiols, phenolics, aldehydes, fatty acids, esters, and so forth. CONCLUSION: Plants widely used as antimalarials by the Tetun ethnic people is proven to have antiplasmodial activity.