Engineering miniature CRISPR-Cas Un1Cas12f1 for efficient base editing
Y. Hu, Linxiao Han, Qiqin Mo, Zengming Du, Wei Jiang, Xia Wu, Jing Zheng, Xiao Xiao, Yadong Sun, Hanhui Ma
Abstract
Publisher of over 50 scientific journals across the life, physical, earth, and health sciences, both independently and in partnership with scientific societies including Cell, Neuron, Immunity, Current Biology, AJHG, and the Trends Journals.
Topics & Concepts
CRISPRBase (topology)Guide RNASubgenomic mRNABase pairComputational biologyGenome editingCas9Vector (molecular biology)Stop codonRNAGeneComputer scienceBiologyGeneticsRecombinant DNAMathematicsMathematical analysisCRISPR and Genetic EngineeringRNA regulation and diseaseVirus-based gene therapy research