Design, synthesis and biological evaluation of novel thiosemicarbazone-indole derivatives targeting prostate cancer cells
Zhangxu He, Jin‐Ling Huo, Yunpeng Gong, Qi An, Xin Zhang, Hui Qiao, Feifei Yang, Xinhui Zhang, Le-Min Jiao, Hong‐Min Liu, Liying Ma, Wen Zhao
Topics & Concepts
ChemistryProstate cancerIC50In vivoApoptosisCancer researchCancerCancer cellLead compoundIndole testStructure–activity relationshipPharmacologyIn vitroStereochemistryBiochemistryInternal medicineBiologyMedicineBiotechnologySynthesis and biological activityCancer Mechanisms and TherapyMetal complexes synthesis and properties