Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages
Po‐Chih Shen, Shih‐Hao Huang, Zi‐Miao Liu, Cheng‐Chang Lu, Shih‐Hsiang Chou, Yin–Chun Tien, Yin–Chun Tien
Topics & Concepts
SuraminCartilageInflammationAggrecanOsteoarthritisCancer researchPharmacologyChemistryChondrocyteArthritisCell biologyImmunologyMedicineBiologyIn vitroPathologyBiochemistryAnatomyArticular cartilageAlternative medicineOsteoarthritis Treatment and MechanismsCytokine Signaling Pathways and InteractionsChemokine receptors and signaling