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Treatment-resistant dermatophytosis: A representative case highlighting an emerging public health threat

David X Gu, Michael M. Hatch, Mahmoud A. Ghannoum, Boni E. Elewski

2020JAAD Case Reports44 citationsDOIOpen Access PDF

Abstract

Treatment-resistant dermatophytosis caused by Trichophyton rubrum has emerged as a global public health threat, particularly in endemic areas like India. However, few, if any such cases, have been reported in the United States. We report a representative case and discuss our experience treating several patients with extensive T rubrum tinea corporis that persisted despite prolonged treatment with systemic and topical agents, including oral terbinafine. We have witnessed an increasing number of treatment-resistant cases in our clinic over the last 5 years, but to our knowledge, there are no reported cases in the United States.

Topics & Concepts

Trichophyton rubrumMedicineTerbinafineDermatologyTinea capitisPublic healthDermatophyteAntifungalPathologyItraconazoleNail Diseases and TreatmentsFungal Infections and StudiesPlant Pathogens and Fungal Diseases
Treatment-resistant dermatophytosis: A representative case highlighting an emerging public health threat | Litcius