Treatment-resistant dermatophytosis: A representative case highlighting an emerging public health threat
David X Gu, Michael M. Hatch, Mahmoud A. Ghannoum, Boni E. Elewski
Abstract
Treatment-resistant dermatophytosis caused by Trichophyton rubrum has emerged as a global public health threat, particularly in endemic areas like India. However, few, if any such cases, have been reported in the United States. We report a representative case and discuss our experience treating several patients with extensive T rubrum tinea corporis that persisted despite prolonged treatment with systemic and topical agents, including oral terbinafine. We have witnessed an increasing number of treatment-resistant cases in our clinic over the last 5 years, but to our knowledge, there are no reported cases in the United States.
Topics & Concepts
Trichophyton rubrumMedicineTerbinafineDermatologyTinea capitisPublic healthDermatophyteAntifungalPathologyItraconazoleNail Diseases and TreatmentsFungal Infections and StudiesPlant Pathogens and Fungal Diseases